粉體行業在線展覽
粉體行業在線展覽
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量子科學儀器貿易（北京）有限公司
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3D單分子熒光成像系統 |
abbelight SAFe360是一款基于單分子定位的顯微成像（SMLM）的3D單分子成像系統，它獨有的DAISY技術整合了散光技術和超臨界角光技術，能夠極大的提高定位精度，達到**的xyz同時15nm的定位精度，可以提供清晰度**的三維的亞細胞結構圖像，**同時四色成像觀測，可以實時研究不同的結構功能蛋白的共定位信息，在單分子水平研究分子動力學反應以及細胞間的相互作用等。
3D單分子熒光成像系統-SAFe 360
設備參數 |
+ 成像模式：PALM、STORM、PAINT、smFRET 、SPT
+ 光源模式：Epi、TIRF、HILO
+ **分辨率：15 nm的XYZ軸分辨率
+ 超大視野：200 × 200 μm2的視野
+ 一次可同時采集1.2 μm深度圖像信息
+ **圖像深度：10 μm
+ 實時漂移矯正
+ **四色同時成像
+ 活細胞成像模式
加裝 | TIRF PALM STORM SPT smFRET ...... | 兼容 | Confocal Spinning-Desk Widefield SIM STED |
Now We See......
3D線粒體結構 | 核孔復合物 |
| 老鼠海馬神經元 | 微管蛋白網絡 |
配套試劑
Smart kit | Compatible dyes |
• 10 doses per box • 200 μL per dose • 30 sec prepartion • 2 months in a fridge • 2 weeks on sample | • Atto 488， WGA-AF®488 • AF®532， CF®532， Cy3b • AF®555， AF®594， CF®555， AF®568， CF®568， Cy5， MemBriteTM 568， TMR • AF®647， CF®647， AF®680， CF®680， MemBriteTM 640， Actin-stain 670， SiR647 |
發表文獻列表
[1] Cabriel， Clément， et al. "Combining 3D single molecule localization strategies for reproducible bioimaging." Nature communications 10.1 (2019): 1980.
[2] Woodhams， Stephen G.， et al. "Cell type–specific super-resolution imaging reveals an increase in calcium-permeable AMPA receptors at spinal peptidergic terminals as an anatomical correlate of inflammatory pain." Pain 160.11 (2019): 2641-2650.
[3] Belkahla， Hanen， et al. "Carbon dots， a powerful non-toxic support for bioimaging by fluorescence nanoscopy and eradication of bacteria by photothermia." Nanoscale Advances (2019).
[4] Denis， Kevin， et al. "Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease." Nature microbiology 4.6 (2019): 972.
[5] Szabo， Quentin， et al. "TADs are 3D structural units of higher-order chromosome organization in Drosophila." Science advances 4.2 (2018): eaar8082.
[6] Boudjemaa， Rym， et al. "Impact of bacterial membrane fatty acid composition on the failure of daptomycin to kill Staphylococcus aureus." Antimicrobial agents and chemotherapy 62.7 (2018): e00023-18.
[7] Culley， Sian， et al. "Quantitative mapping and minimization of super-resolution optical imaging artifacts." Nature methods 15.4 (2018): 263.
[8] Berger， Stephen L.， et al. "Localized myosin II activity regulates assembly and plasticity of the axon initial segment." Neuron 97.3 (2018): 555-570.
[9] Cabriel， Clément， et al. "Aberration-accounting calibration for 3D single-molecule localization microscopy." Optics letters 43.2 (2018): 174-177.
[10] Bouissou， Ana?s， et al. "Podosome force generation machinery: a local balance between protrusion at the core and traction at the ring." ACS nano 11.4 (2017): 4028-4040.
[11] Sellés， Julien， et al. "Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy." Scientific reports 7.1 (2017): 14732.
[12] Bourg， Nicolas， et al. "Direct optical nanoscopy with axially localized detection." Nature Photonics 9.9 (2015): 587.
